Largest study of gay brothers homes in on ‘gay genes’

A genetic analysis of 409 pairs of gay brothers, including sets of twins, has provided the strongest evidence yet that gay people are born gay. The study clearly links sexual orientation in men with two regions of the human genome that have been implicated before, one on the X chromosome and one on chromosome 8.

The finding is an important contribution to mounting evidence that being gay is biologically determined rather than a lifestyle choice. In some countries, such as Uganda, being gay is still criminalised, and some religious groups believe that gay people can be “treated” to make them straight.

“It erodes the notion that sexual orientation is a choice,” says study leader Alan Sanders of the NorthShore Research Institute in Evanston, Illinois.

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